rs6855911
| Orientation | plus |
| Stabilized | plus |
| Geno | Mag | Summary |
|---|---|---|
| (A;A) | 2 | normal, but increased risk of gout |
| (A;G) | 2 | 0.62x decreased risk for gout |
| (G;G) | 2 | rare, but 0.62x decreased risk for gout |
| Reference | GRCh38 38.1/141 |
| Chromosome | 4 |
| Position | 9934286 |
| Gene | SLC2A9 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs6855911 |
| dbSNP (classic) | rs6855911 |
| ClinGen | rs6855911 |
| ebi | rs6855911 |
| HLI | rs6855911 |
| Exac | rs6855911 |
| Gnomad | rs6855911 |
| Varsome | rs6855911 |
| LitVar | rs6855911 |
| Map | rs6855911 |
| PheGenI | rs6855911 |
| Biobank | rs6855911 |
| 1000 genomes | rs6855911 |
| hgdp | rs6855911 |
| ensembl | rs6855911 |
| geneview | rs6855911 |
| scholar | rs6855911 |
| rs6855911 | |
| pharmgkb | rs6855911 |
| gwascentral | rs6855911 |
| openSNP | rs6855911 |
| 23andMe | rs6855911 |
| SNPshot | rs6855911 |
| SNPdbe | rs6855911 |
| MSV3d | rs6855911 |
| GWAS Ctlg | rs6855911 |
| GMAF | 0.2567 |
| Max Magnitude | 2 |
| ? | (A;A) (A;G) (G;G) | 28 |
|---|---|---|
|
| ||
[PMID 17997608
] risk for cardiovascular morbidity and mortality rs6855911 (p = 1.84E-16)
[PMID 18398472] although no risk for coronary artery disease or myocardial infarction was observed, rs6855911 was associated with gout. The minor allele had a protective effect, with an allelic odds ratio of 0.62 (CI: 0.52-0.75, p = 3.2x10(-7)).
| GWAS | |
|---|---|
| SNP | rs6855911 |
| PubMedID | [PMID 17997608]
|
| Condition | Serum urate |
| Gene | GLUT9 |
| Risk Allele | A |
| pValue | 2.00E-016 |
| OR | 0.32 |
| 95% CI | NR) mg/dl highe |
[PMID 19890391] Common polymorphisms influencing serum uric Acid levels contribute to susceptibility to gout, but not to coronary artery disease
[PMID 18487473] Sex-specific association of the putative fructose transporter SLC2A9 variants with uric acid levels is modified by BMI.
[PMID 18606621] SLC2A9--a fructose transporter identified as a novel uric acid transporter.
[PMID 18852197] Metabolic and cardiovascular traits: an abundance of recently identified common genetic variants.
[PMID 19679263] Using new tools to define the genetic underpinnings of risky traits associated with coronary artery disease: the SardiNIA study.
[PMID 20053405] Sex and age interaction with genetic association of atherogenic uric acid concentrations.
[PMID 20972595] Association of an intronic SNP of SLC2A9 gene with serum uric acid levels in the Chinese male Han population by high-resolution melting method.
[PMID 22723994] Serum uric acid and adiposity: deciphering causality using a bidirectional Mendelian randomization approach
[PMID 27511497] Association analysis of five SNP variants with gout in the Minnan population in China.
