rs686
| Orientation | plus |
| Stabilized | plus |
| Geno | Mag | Summary |
|---|---|---|
| (G;G) | 0 |
| Make rs686(A;A) |
| Make rs686(A;G) |
| Reference | GRCh38 38.1/141 |
| Chromosome | 5 |
| Position | 175441697 |
| Gene | DRD1 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs686 |
| dbSNP (classic) | rs686 |
| ClinGen | rs686 |
| ebi | rs686 |
| HLI | rs686 |
| Exac | rs686 |
| Gnomad | rs686 |
| Varsome | rs686 |
| LitVar | rs686 |
| Map | rs686 |
| PheGenI | rs686 |
| Biobank | rs686 |
| 1000 genomes | rs686 |
| hgdp | rs686 |
| ensembl | rs686 |
| geneview | rs686 |
| scholar | rs686 |
| rs686 | |
| pharmgkb | rs686 |
| gwascentral | rs686 |
| openSNP | rs686 |
| 23andMe | rs686 |
| SNPshot | rs686 |
| SNPdbe | rs686 |
| MSV3d | rs686 |
| GWAS Ctlg | rs686 |
| GMAF | 0.382 |
| Max Magnitude | 0 |
| ? | (A;A) (A;G) (G;G) | 28 |
|---|---|---|
|
| ||
Implicated as part of a haplotype of the dopamine D1 receptor DRD1 gene associated with autism spectrum disorders in families having only affected males. The haplotype is rs265981(C)-rs4532(A)-rs686(T) as published, though not necessarily as oriented in dbSNP.[PMID 18205172]
[PMID 20456319] Association of polymorphisms in the BDNF, DRD1 and DRD3 genes with tobacco smoking in schizophrenia
[PMID 18092181] Significant association of DRD1 with nicotine dependence.
[PMID 18341651] A haplotype of the DRD1 gene is associated with alcohol dependence.
[PMID 18937842
] The influence of serotonin- and other genes on impulsive behavioral aggression and cognitive impulsivity in children with attention-deficit/hyperactivity disorder (ADHD): Findings from a family-based association test (FBAT) analysis.
[PMID 19135651] Differential allelic expression of dopamine D1 receptor gene (DRD1) is modulated by microRNA miR-504.
[PMID 19500151] Heroin addiction in African Americans: a hypothesis-driven association study.
[PMID 21332319] Gene-gene interaction analyses between NMDA receptor subunit and dopamine receptor gene variants and clozapine response.
[PMID 21955727] An association study between dopamine D1 receptor gene polymorphisms and the risk of schizophrenia.
[PMID 22574669] Dopamine receptors D1 and D2 are related to observed maternal behavior.
