rs699473
| Orientation | plus |
| Stabilized | plus |
| Geno | Mag | Summary |
|---|---|---|
| (C;C) | 1.5 | ~1.5x increased brain tumor risk |
| (C;T) | 1.5 | ~1.5x increased brain tumor risk |
| (T;T) | 1 | Normal brain tumor risk |
| Reference | GRCh38 38.1/141 |
| Chromosome | 4 |
| Position | 24795181 |
| Gene | SOD3 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs699473 |
| dbSNP (classic) | rs699473 |
| ClinGen | rs699473 |
| ebi | rs699473 |
| HLI | rs699473 |
| Exac | rs699473 |
| Gnomad | rs699473 |
| Varsome | rs699473 |
| LitVar | rs699473 |
| Map | rs699473 |
| PheGenI | rs699473 |
| Biobank | rs699473 |
| 1000 genomes | rs699473 |
| hgdp | rs699473 |
| ensembl | rs699473 |
| geneview | rs699473 |
| scholar | rs699473 |
| rs699473 | |
| pharmgkb | rs699473 |
| gwascentral | rs699473 |
| openSNP | rs699473 |
| 23andMe | rs699473 |
| SNPshot | rs699473 |
| SNPdbe | rs699473 |
| MSV3d | rs699473 |
| GWAS Ctlg | rs699473 |
| GMAF | 0.45 |
| Max Magnitude | 1.5 |
| ? | (C;C) (C;T) (T;T) | 28 |
|---|---|---|
|
| ||
A study of non-Hispanic Caucasians with various types of brain tumors concluded that there was an increased risk of glioma (odds ratio 1.3, CI: 1.0-1.7) and meningioma (odds ratio 1.7, CI: 1.1-2.7) associated with the rs699473(C) allele.[PMID 18682580
]
[PMID 21351093] Association of superoxide dismutases and NAD(P)H quinone oxidoreductases with prognosis of patients with breast carcinomas
[PMID 18778477] Genomic variation in myeloma: design, content, and initial application of the Bank On A Cure SNP Panel to detect associations with progression-free survival.
[PMID 18948423] Extracellular superoxide dismutase haplotypes are associated with acute lung injury and mortality.
[PMID 18971527] A haplotype-based case-control study examining human extracellular superoxide dismutase gene and essential hypertension.
[PMID 19200140] Association of extracellular superoxide dismutase gene with cerebral infarction in women: a haplotype-based case-control study.
[PMID 19318538] Superoxide dismutase 3, extracellular (SOD3) variants and lung function.
[PMID 19505917] Lead exposure, polymorphisms in genes related to oxidative stress, and risk of adult brain tumors.
[PMID 26585352] Associations between circulating carotenoids, genomic instability and the risk of high-grade prostate cancer
