rs7193144
| Orientation | plus |
| Stabilized | plus |
| Make rs7193144(C;C) |
| Make rs7193144(C;T) |
| Make rs7193144(T;T) |
| Reference | GRCh38 38.1/141 |
| Chromosome | 16 |
| Position | 53776774 |
| Gene | FTO |
| is a | snp |
| is | mentioned by |
| dbSNP | rs7193144 |
| dbSNP (classic) | rs7193144 |
| ClinGen | rs7193144 |
| ebi | rs7193144 |
| HLI | rs7193144 |
| Exac | rs7193144 |
| Gnomad | rs7193144 |
| Varsome | rs7193144 |
| LitVar | rs7193144 |
| Map | rs7193144 |
| PheGenI | rs7193144 |
| Biobank | rs7193144 |
| 1000 genomes | rs7193144 |
| hgdp | rs7193144 |
| ensembl | rs7193144 |
| geneview | rs7193144 |
| scholar | rs7193144 |
| rs7193144 | |
| pharmgkb | rs7193144 |
| gwascentral | rs7193144 |
| openSNP | rs7193144 |
| 23andMe | rs7193144 |
| SNPshot | rs7193144 |
| SNPdbe | rs7193144 |
| MSV3d | rs7193144 |
| GWAS Ctlg | rs7193144 |
| GMAF | 0.331 |
| Max Magnitude | 0 |
| ? | (C;C) (C;T) (T;T) | 28 |
|---|---|---|
|
| ||
This SNP is in a linkage block in the FTO gene with rs1121980; see rs1121980 for the association of this block with early onset obesity since it showed the strongest association.[PMID 18159244
] The risk allele is C.
[PMID 18379722] Variations in the FTO gene are associated with severe obesity in the Japanese.
[PMID 18445669] Lack of association of fatness-related FTO gene variants with energy expenditure or physical activity.
[PMID 18487448] Common variation in the fat mass and obesity-associated (FTO) gene confers risk of obesity and modulates BMI in the Chinese population.
[PMID 18599522] FTO variants are associated with obesity in the Chinese and Malay populations in Singapore.
[PMID 19005641] FTO gene variants are strongly associated with type 2 diabetes in South Asian Indians.
[PMID 19008344] Association analysis of variation in/near FTO, CDKAL1, SLC30A8, HHEX, EXT2, IGF2BP2, LOC387761, and CDKN2B with type 2 diabetes and related quantitative traits in Pima Indians.
[PMID 20017965] Identifying association under a previous linkage peak on chromosome 16 for body mass index using cross-sectional and longitudinal data of the Framingham Heart Study.
[PMID 21175269] Genetic variations in the FTO gene are associated with type 2 diabetes and obesity in south Indians (CURES-79).
