rs7297610

Orientation

plus

Stabilized

plus

Geno	Mag	Summary
(C;C)	0	common in clinvar

Make rs7297610(C;T)

Make rs7297610(T;T)

Reference

GRCh38 38.1/141

Chromosome

12

Position

69430244

is a	snp
is	mentioned by
dbSNP	rs7297610
dbSNP (classic)	rs7297610
ClinGen	rs7297610
ebi	rs7297610
HLI	rs7297610
Exac	rs7297610
Gnomad	rs7297610
Varsome	rs7297610
LitVar	rs7297610
Map	rs7297610
PheGenI	rs7297610
Biobank	rs7297610
1000 genomes	rs7297610
hgdp	rs7297610
ensembl	rs7297610
geneview	rs7297610
scholar	rs7297610
google	rs7297610
pharmgkb	rs7297610
gwascentral	rs7297610
openSNP	rs7297610
23andMe	rs7297610
SNPshot	rs7297610
SNPdbe	rs7297610
MSV3d	rs7297610
GWAS Ctlg	rs7297610

GMAF

0.1061

Max Magnitude

0

?	(C;C) (C;T) (T;T)	28

GWAS
SNP	rs317689,rs315135,rs7297610
PubMedID	[PMID 18591461]
Condition	Response to diuretic therapy
Gene	LYZ, YEATS4, FRS2
Risk Allele	e
pValue	6.00E-006
OR	NA
95% CI

[PMID 22350108] Association of chromosome 12 locus with antihypertensive response to hydrochlorothiazide may involve differential YEATS4 expression.

ClinVar
Risk	rs7297610(T;T)
Alt	rs7297610(T;T)
Reference	Rs7297610(C;C)
Significance	Drug-response
Disease	hydrochlorothiazide response - Efficacy
Variation	info
Gene
CLNDBN	hydrochlorothiazide response - Efficacy
Reversed	0
HGVS	NC_000012.11:g.69824024C>T
CLNSRC	PharmGKB Clinical Annotation
CLNACC	RCV000211271.1,