rs730012
| Orientation | plus |
| Stabilized | plus |
| Geno | Mag | Summary |
|---|---|---|
| (A;A) | 0 | common in clinvar |
| Make rs730012(A;C) |
| Make rs730012(C;C) |
| Reference | GRCh38 38.1/141 |
| Chromosome | 5 |
| Position | 179793637 |
| Gene | LTC4S |
| is a | snp |
| is | mentioned by |
| dbSNP | rs730012 |
| dbSNP (classic) | rs730012 |
| ClinGen | rs730012 |
| ebi | rs730012 |
| HLI | rs730012 |
| Exac | rs730012 |
| Gnomad | rs730012 |
| Varsome | rs730012 |
| LitVar | rs730012 |
| Map | rs730012 |
| PheGenI | rs730012 |
| Biobank | rs730012 |
| 1000 genomes | rs730012 |
| hgdp | rs730012 |
| ensembl | rs730012 |
| geneview | rs730012 |
| scholar | rs730012 |
| rs730012 | |
| pharmgkb | rs730012 |
| gwascentral | rs730012 |
| openSNP | rs730012 |
| 23andMe | rs730012 |
| SNPshot | rs730012 |
| SNPdbe | rs730012 |
| MSV3d | rs730012 |
| GWAS Ctlg | rs730012 |
| GMAF | 0.1993 |
| Max Magnitude | 0 |
| ? | (A;A) (A;C) (C;C) | 28 |
|---|---|---|
|
| ||
[PMID 15726497
] Gene-environment interaction effects on the development of immune responses in the 1st year of life.
[PMID 18366797] Influence of leukotriene gene polymorphisms on chronic rhinosinusitis.
[PMID 19131662] A meta-analysis of candidate gene polymorphisms and ischemic stroke in 6 study populations: association of lymphotoxin-alpha in nonhypertensive patients.
[PMID 19214143] 5-lipoxygenase pharmacogenetics in asthma: overlap with Cys-leukotriene receptor antagonist loci.
[PMID 19223558] Polymorphic variation in NFKB1 and other aspirin-related genes and risk of Hodgkin lymphoma.
[PMID 19263529] Genetic risk factors in recurrent venous thromboembolism: A multilocus, population-based, prospective approach.
[PMID 19330901] Association of 77 polymorphisms in 52 candidate genes with blood pressure progression and incident hypertension: the Women's Genome Health Study.
[PMID 19559392] A candidate gene association study of 77 polymorphisms in migraine.
[PMID 19665766] Genetics and pharmacogenetics of the leukotriene pathway.
[PMID 20031584] Genetics of atherothrombotic and lacunar stroke.
[PMID 20592916] Pharmacogenomic approaches to asthma treatment.
[PMID 23079278] Genetic variation in members of the leukotrienes biosynthesis pathway confers risk of ischemic stroke in Eastern Han Chinese
[PMID 23663310] Investigating highly replicated asthma genes as candidate genes for allergic rhinitis.
| ClinVar | |
|---|---|
| Risk | rs730012(C;C) |
| Alt | rs730012(C;C) |
| Reference | Rs730012(A;A) |
| Significance | Drug-response |
| Disease | aspirin response - Toxicity/ADR |
| Variation | info |
| Gene | LTC4S |
| CLNDBN | aspirin response - Toxicity/ADR |
| Reversed | 0 |
| HGVS | NC_000005.9:g.179220638A>C |
| CLNSRC | PharmGKB Clinical Annotation |
| CLNACC | RCV000211358.1, |
