rs7538490
From SNPedia
| Orientation | plus |
| Stabilized | plus |
| Make rs7538490(C;C) |
| Make rs7538490(C;T) |
| Make rs7538490(T;T) |
| Reference | GRCh38 38.1/141 |
| Chromosome | 1 |
| Position | 162121540 |
| Gene | LOC105371475, NOS1AP |
| is a | snp |
| is | mentioned by |
| dbSNP | rs7538490 |
| dbSNP (classic) | rs7538490 |
| ClinGen | rs7538490 |
| ebi | rs7538490 |
| HLI | rs7538490 |
| Exac | rs7538490 |
| Gnomad | rs7538490 |
| Varsome | rs7538490 |
| LitVar | rs7538490 |
| Map | rs7538490 |
| PheGenI | rs7538490 |
| Biobank | rs7538490 |
| 1000 genomes | rs7538490 |
| hgdp | rs7538490 |
| ensembl | rs7538490 |
| geneview | rs7538490 |
| scholar | rs7538490 |
| rs7538490 | |
| pharmgkb | rs7538490 |
| gwascentral | rs7538490 |
| openSNP | rs7538490 |
| 23andMe | rs7538490 |
| SNPshot | rs7538490 |
| SNPdbe | rs7538490 |
| MSV3d | rs7538490 |
| GWAS Ctlg | rs7538490 |
| GMAF | 0.3343 |
| Max Magnitude | 0 |
| ? | (C;C) (C;T) (T;T) | 28 |
|---|---|---|
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| ||
The T-allele of NOS1AP rs3020781 was previously reported to be strongly associated with type-2 diabetes in various European-descent populations comprising a total of 2,198 individuals with a combined odds ratio (OR) of 1.53 [1.28-1.81].
However, in a combined study sample comprising a total of 16,801 and 16,913 individuals from Denmark, no significant association was found to diabetes or obesity.[PMID 19111066
]
[PMID 19389826] Linkage disequilibrium mapping of the replicated type 2 diabetes linkage signal on chromosome 1q
