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rs761100

From SNPedia

Orientationminus
Stabilizedminus
Geno Mag Summary
(G;G) 1 higher risk for dyslexia
(G;T) 0 normal risk
(T;T) 0 normal risk
ReferenceGRCh38 38.1/141
Chromosome6
Position24632414
GeneKIAA0319
is asnp
is mentioned by
dbSNPrs761100
dbSNP (classic)rs761100
ClinGenrs761100
ebirs761100
HLIrs761100
Exacrs761100
Gnomadrs761100
Varsomers761100
LitVarrs761100
Maprs761100
PheGenIrs761100
Biobankrs761100
1000 genomesrs761100
hgdprs761100
ensemblrs761100
geneviewrs761100
scholarrs761100
googlers761100
pharmgkbrs761100
gwascentralrs761100
openSNPrs761100
23andMers761100
SNPshotrs761100
SNPdbers761100
MSV3drs761100
GWAS Ctlgrs761100
GMAF0.3173
Max Magnitude1
? (G;G) (G;T) (T;T) 28


The more common allele of rs761100 has been linked to increased risk for developmental dyslexia in a study of ~300 British families. While odds ratios were not reported, the significance was reported as p=0.02.[PMID 17033633]

[PMID 19997522OA-icon.png] Convergent genetic linkage and associations to language, speech and reading measures in families of probands with Specific Language Impairment.

Developmental Dyslexia