rs766173

minus

Geno	Mag	Summary
(G;G)	2
(T;T)	0	common in complete genomics

Make rs766173(G;T)

Reference

GRCh38 38.1/142

Chromosome

13

Position

32332343

Gene

BRCA2

is a	snp
is	mentioned by
dbSNP	rs766173
dbSNP (classic)	rs766173
ClinGen	rs766173
ebi	rs766173
HLI	rs766173
Exac	rs766173
Gnomad	rs766173
Varsome	rs766173
LitVar	rs766173
Map	rs766173
PheGenI	rs766173
Biobank	rs766173
1000 genomes	rs766173
hgdp	rs766173
ensembl	rs766173
geneview	rs766173
scholar	rs766173
google	rs766173
pharmgkb	rs766173
gwascentral	rs766173
openSNP	rs766173
23andMe	rs766173
SNPshot	rs766173
SNPdbe	rs766173
MSV3d	rs766173
GWAS Ctlg	rs766173

GMAF

0.05831

Max Magnitude

2

?

(G;G) (G;T) (T;T)

28

This SNP, a variant in the BRCA2 gene, is 1 of 25 SNPs reported to represent independently minor, but cumulatively significant, increased risk for breast cancer. [PMID 17341484]

For details of all 25 SNPs in this group, along with the two methods used to calculate overall risk estimates for breast cancer, refer to the SNPedia breast cancer entry.

For this particular SNP, the risk (minor) allele is (G).

ClinVar
Risk	rs766173(C;C) Rs766173(G;G)
Alt	rs766173(C;C) Rs766173(G;G)
Reference	Rs766173(T;T)
Significance	Probable-non-pathogenic
Disease	not provided Breast-ovarian cancer not specified Hereditary cancer-predisposing syndrome Fanconi anemia Hereditary breast and ovarian cancer syndrome Familial cancer of breast
Variation	info
Gene	BRCA2
CLNDBN	not provided Breast-ovarian cancer, familial 2 not specified Hereditary cancer-predisposing syndrome Fanconi anemia Hereditary breast and ovarian cancer syndrome Familial cancer of breast
Reversed	1
HGVS	NC_000013.10:g.32906480A>C; NC_000013.10:g.32906480A>G
CLNSRC	Inc.
CLNACC	RCV000034465.3, RCV000112858.4, RCV000120305.5, RCV000130996.3, RCV000351416.1, RCV000393165.2, RCV000470594.1, RCV000031759.4, RCV000045592.4, RCV000164485.2, RCV000441052.1,

[PMID 16857995 ] Risk of non-Hodgkin lymphoma (NHL) in relation to germline variation in DNA repair and related genes.