rs7757037

plus

Geno	Mag	Summary
(A;A)		0.63x decreased risk for bipolar disorder
(A;G)		0.68x decreased risk for bipolar disorder
(G;G)	0	normal

Reference

GRCh38 38.1/141

Chromosome

6

Position

35580459

Gene	FKBP5, LOC101929309

is a	snp
is	mentioned by
dbSNP	rs7757037
dbSNP (classic)	rs7757037
ClinGen	rs7757037
ebi	rs7757037
HLI	rs7757037
Exac	rs7757037
Gnomad	rs7757037
Varsome	rs7757037
LitVar	rs7757037
Map	rs7757037
PheGenI	rs7757037
Biobank	rs7757037
1000 genomes	rs7757037
hgdp	rs7757037
ensembl	rs7757037
geneview	rs7757037
scholar	rs7757037
google	rs7757037
pharmgkb	rs7757037
gwascentral	rs7757037
openSNP	rs7757037
23andMe	rs7757037
SNPshot	rs7757037
SNPdbe	rs7757037
MSV3d	rs7757037
GWAS Ctlg	rs7757037

GMAF

0.4991

Max Magnitude

0

?

(A;A) (A;G) (G;G)

28

rs7757037, a SNP in the FKBP5 gene, is associated with increased risk for bipolar disorder in a study of 500+ Caucasian patients.

The most common allele, rs7757037(G), was associated with highest risk. Giving that allele a relative odds ratio of 1.0, the odds for the (A;G) and (A;A) genotypes were 0.68x (CI:0.53-0.87, p=0.007) and 0.63x (CI: 0.45-0.89, p=0.007).[PMID 18180755 ]