rs80357777

minus

Geno	Mag	Summary
(-;AAGC)	6	BRCA1 variant considered pathogenic for breast cancer
(AAGC;AAGC)	0	common/normal
(CAAG;CAAG)	0	common in clinvar

Make rs80357777(-;-)

Reference

GRCh38 38.1/142

Chromosome

17

Position

43092200

Gene

BRCA1

is a	snp
is	mentioned by
dbSNP	rs80357777
dbSNP (classic)	rs80357777
ClinGen	rs80357777
ebi	rs80357777
HLI	rs80357777
Exac	rs80357777
Gnomad	rs80357777
Varsome	rs80357777
LitVar	rs80357777
Map	rs80357777
PheGenI	rs80357777
Biobank	rs80357777
1000 genomes	rs80357777
hgdp	rs80357777
ensembl	rs80357777
geneview	rs80357777
scholar	rs80357777
google	rs80357777
pharmgkb	rs80357777
gwascentral	rs80357777
openSNP	rs80357777
23andMe	rs80357777
SNPshot	rs80357777
SNPdbe	rs80357777
MSV3d	rs80357777
GWAS Ctlg	rs80357777

Status

Merged into rs80357701

Max Magnitude

6

rs80357777, also known as 3447del4, c.3328_3331delAAGC and p.Lys1110_Gln1111?fs, is a variant in the BRCA1 gene considered pathogenic for breast cancer in ClinVar.

ClinVar
Risk
Alt
Reference	Rs80357777(CAAG;CAAG)
Significance	Pathogenic
Disease	Breast-ovarian cancer not provided Hereditary cancer-predisposing syndrome Hereditary breast and ovarian cancer syndrome
Variation	info
Gene	BRCA1
CLNDBN	Breast-ovarian cancer, familial 1 not provided Hereditary cancer-predisposing syndrome Hereditary breast and ovarian cancer syndrome
Reversed	1
HGVS	NC_000017.10:g.41244214_41244217delCTTG
CLNSRC	Breast Cancer Information Core (BRCA1)
CLNACC	RCV000031104.10, RCV000048151.5, RCV000131812.3, RCV000195363.2,