rs8050910

Orientation

plus

Stabilized

plus

Make rs8050910(G;G)

Make rs8050910(G;T)

Make rs8050910(T;T)

Reference

GRCh38 38.1/141

Chromosome

16

Position

85105567

Gene

FAM92B

is a	snp
is	mentioned by
dbSNP	rs8050910
dbSNP (classic)	rs8050910
ClinGen	rs8050910
ebi	rs8050910
HLI	rs8050910
Exac	rs8050910
Gnomad	rs8050910
Varsome	rs8050910
LitVar	rs8050910
Map	rs8050910
PheGenI	rs8050910
Biobank	rs8050910
1000 genomes	rs8050910
hgdp	rs8050910
ensembl	rs8050910
geneview	rs8050910
scholar	rs8050910
google	rs8050910
pharmgkb	rs8050910
gwascentral	rs8050910
openSNP	rs8050910
23andMe	rs8050910
SNPshot	rs8050910
SNPdbe	rs8050910
MSV3d	rs8050910
GWAS Ctlg	rs8050910

GMAF

0.4348

Max Magnitude

0

?	(G;G) (G;T) (T;T)	28

Rs8050910
PubMed	[PMID 17435756]
Affy Probeset	SNP_A-2197527
Affy Orientation	reverse
On GW 5.0	1
Alleles A/B	A/C
Ancestral	T
Population	EU
Allele	T
Case Freq.	0.61
Control Freq.	0.54
Odds Ratio Het
Odds Ratio Hom
Odds Ratio All	1.19
Disease	Crohn's disease (CD)

rs8050910 increases susceptibility to Crohn's disease 1.19 times for carriers of the T allele [PMID 17435756]

[PMID 19262523] rs224136 on chromosome 10q21.1 and variants in PHOX2B, NCF4, and FAM92B are not major genetic risk factors for susceptibility to Crohn's disease in the German population

OMIM	266600
Desc	INFLAMMATORY BOWEL DISEASE 1; IBD1
Variant
Related	also

[PMID 17068223] A genome-wide association study identifies IL23R as an inflammatory bowel disease gene.

[PMID 18580884] Confirmation of association of IRGM and NCF4 with ileal Crohn's disease in a population-based cohort.