rs892086
From SNPedia
| Orientation | minus |
| Stabilized | minus |
| Geno | Mag | Summary |
|---|---|---|
| (A;G) | 0 | |
| (C;C) | 0 | normal |
| (C;T) | 0 | normal |
| (G;G) | 0 | |
| (T;T) | 1.5x increased Alzheimer risk in non-ApoE4 carriers |
| Reference | GRCh38 38.1/141 |
| Chromosome | 19 |
| Position | 10727001 |
| Gene | DNM2 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs892086 |
| dbSNP (classic) | rs892086 |
| ClinGen | rs892086 |
| ebi | rs892086 |
| HLI | rs892086 |
| Exac | rs892086 |
| Gnomad | rs892086 |
| Varsome | rs892086 |
| LitVar | rs892086 |
| Map | rs892086 |
| PheGenI | rs892086 |
| Biobank | rs892086 |
| 1000 genomes | rs892086 |
| hgdp | rs892086 |
| ensembl | rs892086 |
| geneview | rs892086 |
| scholar | rs892086 |
| rs892086 | |
| pharmgkb | rs892086 |
| gwascentral | rs892086 |
| openSNP | rs892086 |
| 23andMe | rs892086 |
| SNPshot | rs892086 |
| SNPdbe | rs892086 |
| MSV3d | rs892086 |
| GWAS Ctlg | rs892086 |
| GMAF | 0.4743 |
| Max Magnitude | 0 |
| ? | (C;C) (C;T) (T;T) | 28 |
|---|---|---|
|
| ||
Carriers with late-onset Alzheimer's disease who have rs892086(T;T) genotypes appear to have less DNM2 mRNA in their brains, according to a study of 429 Japanese patients, and among non-ApoE4 carriers, appear to be at increased risk for developing Alzheimer's disease. The odds ratio reported is 1.53 (CI: 1.08-2.17, p=0.015).[PMID 18236001]
