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From SNPedia
Magnitude 2.5
Repute Bad
Summary Increased surveillance for colorectal cancer recommended
Criteria Gs298/criteria

This genoset detects the ~10% of the population having either 3 or more risk alleles, or 3 at-risk genotypes, at 3 SNPs associated with colorectal cancer; this puts a person at ~3 fold higher risk than a person with 0 risk alleles, and on a par with someone who has a first degree relative with colorectal cancer. As a result, individuals with this genoset might benefit from colorectal detection based either on fecal immunochemical testing or colonoscopy every 5 years starting as early as age 40, according to one study.10.1038/ejhg.2015.72

The 3 SNPs and their risk alleles are: