rs1042058
From SNPedia
| Orientation | plus |
| Stabilized | plus |
| Make rs1042058(C;C) |
| Make rs1042058(C;T) |
| Make rs1042058(T;T) |
| Reference | GRCh38 38.1/142 |
| Chromosome | 10 |
| Position | 30439172 |
| Gene | MAP3K8 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs1042058 |
| dbSNP (classic) | rs1042058 |
| ClinGen | rs1042058 |
| ebi | rs1042058 |
| HLI | rs1042058 |
| Exac | rs1042058 |
| Gnomad | rs1042058 |
| Varsome | rs1042058 |
| LitVar | rs1042058 |
| Map | rs1042058 |
| PheGenI | rs1042058 |
| Biobank | rs1042058 |
| 1000 genomes | rs1042058 |
| hgdp | rs1042058 |
| ensembl | rs1042058 |
| geneview | rs1042058 |
| scholar | rs1042058 |
| rs1042058 | |
| pharmgkb | rs1042058 |
| gwascentral | rs1042058 |
| openSNP | rs1042058 |
| 23andMe | rs1042058 |
| SNPshot | rs1042058 |
| SNPdbe | rs1042058 |
| MSV3d | rs1042058 |
| GWAS Ctlg | rs1042058 |
| GMAF | 0.4284 |
| Max Magnitude | 0 |
| ? | (C;C) (C;T) (T;T) | 28 |
|---|---|---|
|
| ||
| GWAS snp | |
|---|---|
| PMID | [PMID 23128233 ]
|
| Trait | Inflammatory bowel disease |
| Title | Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease. |
| Risk Allele | C |
| P-val | 6E-11 |
| Odds Ratio | 1.08 [1.044-1.106] |
[PMID 18091754] Regional association-based fine-mapping for sodium-lithium countertransport on chromosome 10.
[PMID 26215868] A TPL2 (MAP3K8) disease-risk polymorphism increases TPL2 expression thereby leading to increased pattern recognition receptor-initiated caspase-1 and caspase-8 activation, signalling and cytokine secretion
