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rs10871777

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(A;A) 0 normal
(A;G) 2 adults likely to be 0.22 BMI units higher
(G;G) 2.1 adults likely to be 0.44 BMI units higher
ReferenceGRCh38 38.1/141
Chromosome18
Position60184530
GeneMC4R
is asnp
is mentioned by
dbSNPrs10871777
dbSNP (classic)rs10871777
ClinGenrs10871777
ebirs10871777
HLIrs10871777
Exacrs10871777
Gnomadrs10871777
Varsomers10871777
LitVarrs10871777
Maprs10871777
PheGenIrs10871777
Biobankrs10871777
1000 genomesrs10871777
hgdprs10871777
ensemblrs10871777
geneviewrs10871777
scholarrs10871777
googlers10871777
pharmgkbrs10871777
gwascentralrs10871777
openSNPrs10871777
23andMers10871777
SNPshotrs10871777
SNPdbers10871777
MSV3drs10871777
GWAS Ctlgrs10871777
GMAF0.2277
Max Magnitude2.1
? (A;A) (A;G) (G;G) 28


See rs17782313 for details.



[PMID 19265794OA-icon.png] Investigation of the Locus Near MC4R With Childhood Obesity in Americans of European and African Ancestry

GWAS snp
PMID [PMID 20421936OA-icon.png]
Trait Obesity (extreme)
Title Two new loci for body-weight regulation identified in a joint analysis of genome-wide association studies for early-onset extreme obesity in French and German study groups
Risk Allele G
P-val 6E-11
Odds Ratio 1.22 [1.09-1.37]


[PMID 19553259OA-icon.png] Common body mass index-associated variants confer risk of extreme obesity.

Measures of Obesity


[PMID 23874820OA-icon.png] Evaluation of 41 Candidate Gene Variants for Obesity in the EPIC-Potsdam Cohort by Multi-Locus Stepwise Regression

GWAS snp
PMID [PMID 23563607OA-icon.png]
Trait Obesity
Title Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.
Risk Allele G
P-val 2E-27
Odds Ratio 1.10 [NR]