rs10871777

Orientation

plus

Stabilized

plus

Geno	Mag	Summary
(A;A)	0	normal
(A;G)	2	adults likely to be 0.22 BMI units higher
(G;G)	2.1	adults likely to be 0.44 BMI units higher

Reference

GRCh38 38.1/141

Chromosome

18

Position

60184530

Gene

MC4R

is a	snp
is	mentioned by
dbSNP	rs10871777
dbSNP (classic)	rs10871777
ClinGen	rs10871777
ebi	rs10871777
HLI	rs10871777
Exac	rs10871777
Gnomad	rs10871777
Varsome	rs10871777
LitVar	rs10871777
Map	rs10871777
PheGenI	rs10871777
Biobank	rs10871777
1000 genomes	rs10871777
hgdp	rs10871777
ensembl	rs10871777
geneview	rs10871777
scholar	rs10871777
google	rs10871777
pharmgkb	rs10871777
gwascentral	rs10871777
openSNP	rs10871777
23andMe	rs10871777
SNPshot	rs10871777
SNPdbe	rs10871777
MSV3d	rs10871777
GWAS Ctlg	rs10871777

GMAF

0.2277

Max Magnitude

2.1

?	(A;A) (A;G) (G;G)	28

See rs17782313 for details.

[PMID 19265794] Investigation of the Locus Near MC4R With Childhood Obesity in Americans of European and African Ancestry

GWAS snp
PMID	[PMID 20421936]
Trait	Obesity (extreme)
Title	Two new loci for body-weight regulation identified in a joint analysis of genome-wide association studies for early-onset extreme obesity in French and German study groups
Risk Allele	G
P-val	6E-11
Odds Ratio	1.22 [1.09-1.37]

[PMID 19553259] Common body mass index-associated variants confer risk of extreme obesity.

Measures of Obesity

[PMID 23874820] Evaluation of 41 Candidate Gene Variants for Obesity in the EPIC-Potsdam Cohort by Multi-Locus Stepwise Regression

GWAS snp
PMID	[PMID 23563607]
Trait	Obesity
Title	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.
Risk Allele	G
P-val	2E-27
Odds Ratio	1.10 [NR]