rs1736557

plus

Geno	Mag	Summary
(A;A)	1.1	normal?
(A;G)	0	unlikely to be associated with trimethylaminuria unless as a carrier (if that)
(G;G)	0	common in clinvar

Reference

GRCh38 38.1/141

Chromosome

1

Position

171110939

Gene

FMO3

is a	snp
is	mentioned by
dbSNP	rs1736557
dbSNP (classic)	rs1736557
ClinGen	rs1736557
ebi	rs1736557
HLI	rs1736557
Exac	rs1736557
Gnomad	rs1736557
Varsome	rs1736557
LitVar	rs1736557
Map	rs1736557
PheGenI	rs1736557
Biobank	rs1736557
1000 genomes	rs1736557
hgdp	rs1736557
ensembl	rs1736557
geneview	rs1736557
scholar	rs1736557
google	rs1736557
pharmgkb	rs1736557
gwascentral	rs1736557
openSNP	rs1736557
23andMe	rs1736557
SNPshot	rs1736557
SNPdbe	rs1736557
MSV3d	rs1736557
GWAS Ctlg	rs1736557

Merged from

Rs17858963

GMAF

0.09412

Max Magnitude

1.1

rs1736557, also known as Val257Met, is a SNP in the FMO3 gene. It has been linked to trimethylaminuria; see variant .0002, OMIM 136132.

?

(A;A) (A;G) (G;G)

28

OMIM	136132
Desc
Variant	0002
Related	also

ClinVar
Risk	Rs1736557(A;A)
Alt	Rs1736557(A;A)
Reference	Rs1736557(G;G)
Significance	Other
Disease	Trimethylaminuria not specified
Variation	info
Gene	FMO3
CLNDBN	Trimethylaminuria not specified
Reversed	0
HGVS	NC_000001.10:g.171080080G>A
CLNSRC	OMIM Allelic Variant UniProtKB (protein)
CLNACC	RCV000017698.29, RCV000253910.1,

[PMID 15858076] Discovery of novel flavin-containing monooxygenase 3 (FMO3) single nucleotide polymorphisms and functional analysis of upstream haplotype variants.

[PMID 24165757] The association of cytochrome P450 genetic polymorphisms with sulfolane formation and the efficacy of a busulfan-based conditioning regimen in pediatric patients undergoing hematopoietic stem cell transplantation