rs2287074

plus

Geno	Mag	Summary
(G;G)	0	common in clinvar

Make rs2287074(A;A)

Make rs2287074(A;G)

Reference

GRCh38 38.1/141

Chromosome

16

Position

55493201

Gene

MMP2

is a	snp
is	mentioned by
dbSNP	rs2287074
dbSNP (classic)	rs2287074
ClinGen	rs2287074
ebi	rs2287074
HLI	rs2287074
Exac	rs2287074
Gnomad	rs2287074
Varsome	rs2287074
LitVar	rs2287074
Map	rs2287074
PheGenI	rs2287074
Biobank	rs2287074
1000 genomes	rs2287074
hgdp	rs2287074
ensembl	rs2287074
geneview	rs2287074
scholar	rs2287074
google	rs2287074
pharmgkb	rs2287074
gwascentral	rs2287074
openSNP	rs2287074
23andMe	rs2287074
SNPshot	rs2287074
SNPdbe	rs2287074
MSV3d	rs2287074
GWAS Ctlg	rs2287074

GMAF

0.3494

Max Magnitude

0

?

(A;A) (A;G) (G;G)

28

[PMID 18560213] association of the MMP-2 gene with the development of lacunar stroke. rs1030868, rs2241145, rs2287074, rs2287076, rs7201 showed a significant association with small vessel infarcts (p < 0.05) and rs7201:g.C was identified as an independent risk factor by multivariable logistic regression analysis

[PMID 18359774] Estrogen receptor alpha and matrix metalloproteinase 2 polymorphisms and age-related maculopathy in older women.

[PMID 18787887 ] Genetic variation in candidate osteoporosis genes, bone mineral density, and fracture risk: the study of osteoporotic fractures.

[PMID 19454611 ] Matrix metalloproteinase-2 polymorphisms and breast cancer susceptibility.

[PMID 20157405 ] Matrix Metallopeptidase 2 Gene Polymorphism is Associated with Obesity in Korean Population.

ClinVar
Risk	rs2287074(A;A) rs2287074(C;C)
Alt	rs2287074(A;A) rs2287074(C;C)
Reference	Rs2287074(G;G)
Significance	Non-pathogenic
Disease	Multicentric Osteolysis-Nodulosis-Arthropathy (MONA) Spectrum Disorders
Variation	info
Gene	MMP2
CLNDBN	Multicentric Osteolysis-Nodulosis-Arthropathy (MONA) Spectrum Disorders
Reversed	0
HGVS	NC_000016.9:g.55527113G>A
CLNSRC
CLNACC	RCV000394276.1,