rs3093059
| Orientation | minus |
| Stabilized | minus |
| Geno | Mag | Summary |
|---|---|---|
| (C;C) | 2 | associated with elevated C-reactive protein levels and hypertension |
| Make rs3093059(C;T) |
| Make rs3093059(T;T) |
| Reference | GRCh38 38.1/141 |
| Chromosome | 1 |
| Position | 159715346 |
| Gene | CRP |
| is a | snp |
| is | mentioned by |
| dbSNP | rs3093059 |
| dbSNP (classic) | rs3093059 |
| ClinGen | rs3093059 |
| ebi | rs3093059 |
| HLI | rs3093059 |
| Exac | rs3093059 |
| Gnomad | rs3093059 |
| Varsome | rs3093059 |
| LitVar | rs3093059 |
| Map | rs3093059 |
| PheGenI | rs3093059 |
| Biobank | rs3093059 |
| 1000 genomes | rs3093059 |
| hgdp | rs3093059 |
| ensembl | rs3093059 |
| geneview | rs3093059 |
| scholar | rs3093059 |
| rs3093059 | |
| pharmgkb | rs3093059 |
| gwascentral | rs3093059 |
| openSNP | rs3093059 |
| 23andMe | rs3093059 |
| SNPshot | rs3093059 |
| SNPdbe | rs3093059 |
| MSV3d | rs3093059 |
| GWAS Ctlg | rs3093059 |
| GMAF | 0.1474 |
| Max Magnitude | 2 |
| ? | (C;C) (C;T) (T;T) | 28 |
|---|---|---|
|
| ||
[PMID 21196492] A study of 12,854 Japanese subjects replicated the association between rs3093059 and serum CRP levels (p = 3.5 x 10e-21).
[PMID 16731635] Association study of CRP gene polymorphisms with serum CRP level and cardiovascular risk rs3093059 rs3091244
[PMID 19040303] C-reactive protein gene polymorphisms in biopsy-proven giant cell arteritis from Northwestern Spain
[PMID 21293934] Association of C-reactive Protein Gene Polymorphisms and Colorectal Cancer
| GWAS snp | |
|---|---|
| PMID | [PMID 21196492] |
| Trait | |
| Title | Genome-wide association study for C-reactive protein levels identified pleiotropic associations in the IL6 locus |
| Risk Allele | G |
| P-val | 4E-21 |
| Odds Ratio | 0.1610 [0.13-0.19] unit increase |
[PMID 16723442
] A prospective assessment of the Y402H variant in complement factor H, genetic variants in C-reactive protein, and risk of age-related macular degeneration.
[PMID 17900590] C-reactive protein gene variation and type 2 diabetes mellitus: a case-control study.
[PMID 18216863] Genetic determinants of basal C-reactive protein expression in Filipino systemic lupus erythematosus families.
[PMID 18394581] Bayesian meta-analysis of genetic association studies with different sets of markers.
[PMID 18439548] Loci related to metabolic-syndrome pathways including LEPR,HNF1A, IL6R, and GCKR associate with plasma C-reactive protein: the Women's Genome Health Study.
[PMID 18704199] Comprehensive analysis of CRP, CFH Y402H and environmental risk factors on risk of neovascular age-related macular degeneration.
[PMID 18793001] Genetic variation in C-reactive protein (CRP) gene may be associated with risk of systemic lupus erythematosus and CRP concentrations.
[PMID 19095725] Relation of genetic variation in the gene coding for C-reactive protein with its plasma protein concentrations: findings from the Women's Health Initiative Observational Cohort.
[PMID 19262552] C-reactive protein polymorphisms and genetic susceptibility to ischemic stroke and hemorrhagic stroke in the Chinese Han population.
[PMID 19426506] C-Reactive protein gene variants are associated with postoperative C-reactive protein levels after coronary artery bypass surgery.
[PMID 22875596] Association study of CRP gene and ischemic stroke in a Chinese Han population
[PMID 24862635] Association of CRP gene polymorphisms with serum CRP level and handgrip strength in community-dwelling elders in Taiwan: Taichung Community Health Study for Elders (TCHS-E)
[PMID 25027406] C-reactive protein genetic polymorphisms increase susceptibility to HBV-related hepatocellular carcinoma in a Chinese population
[PMID 26004291] C-reactive protein gene polymorphisms and gene-environment interactions in ischaemic stroke
[PMID 26884882] Genetic polymorphisms of C-reactive protein increase susceptibility to HBV-related hepatocellular carcinoma in a Guangxi male population.
[PMID 28287042] Impact of CRP gene and additional gene-smoking interaction on ischemic stroke in a Chinese Han population.
[PMID 28839172] Genome-wide association study of bronchopulmonary dysplasia: a potential role for variants near the CRP gene.
[PMID 29556849] C-reactive protein (CRP) polymorphisms and haplotypes are associated with SLE susceptibility and activity but not with serum CRP levels in Mexican population.
[PMID 31692152] Association of plasma C-reactive protein with ischemic stroke: A Mendelian randomization study.
[PMID 32214403] Evaluation of single nucleotide polymorphisms in 6 candidate genes and carotid intima-media thickness in community-dwelling residents.
