rs3735273
From SNPedia
| Orientation | minus |
| Stabilized | minus |
| Make rs3735273(A;A) |
| Make rs3735273(A;G) |
| Make rs3735273(G;G) |
| Reference | GRCh38 38.1/141 |
| Chromosome | 7 |
| Position | 50529166 |
| Gene | DDC |
| is a | snp |
| is | mentioned by |
| dbSNP | rs3735273 |
| dbSNP (classic) | rs3735273 |
| ClinGen | rs3735273 |
| ebi | rs3735273 |
| HLI | rs3735273 |
| Exac | rs3735273 |
| Gnomad | rs3735273 |
| Varsome | rs3735273 |
| LitVar | rs3735273 |
| Map | rs3735273 |
| PheGenI | rs3735273 |
| Biobank | rs3735273 |
| 1000 genomes | rs3735273 |
| hgdp | rs3735273 |
| ensembl | rs3735273 |
| geneview | rs3735273 |
| scholar | rs3735273 |
| rs3735273 | |
| pharmgkb | rs3735273 |
| gwascentral | rs3735273 |
| openSNP | rs3735273 |
| 23andMe | rs3735273 |
| SNPshot | rs3735273 |
| SNPdbe | rs3735273 |
| MSV3d | rs3735273 |
| GWAS Ctlg | rs3735273 |
| GMAF | 0.2787 |
| Max Magnitude | 0 |
| ? | (A;A) (A;G) (G;G) | 28 |
|---|---|---|
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per OMIM, Ma et al. (2005) [PMID 15879433] found two different DDC haplotypes associated with nicotine dependence in African Americans and European Americans (with measures of smoking quantity [SQ], heaviness of smoking index [HSI], and the Fagerstrom test for ND [FTND])
- in African Americans, rs921451(T), rs3735273(G), rs1451371(T), rs2060762(G), all three measures sig. associated after correction for multiple testing
- in European Americans, rs921451(T), rs3735273(G), rs1451371(T), rs3757472(G), which showed a sig. assoc. w/ the SQ and FTND score
[PMID 17184203] DOPA decarboxylase gene is associated with nicotine dependence.
