rs3774426
From SNPedia
| Orientation | plus |
| Stabilized | plus |
| Geno | Mag | Summary |
|---|---|---|
| (C;C) | better response to certain calcium channel blockers | |
| (C;T) | normal | |
| (T;T) | normal |
| Reference | GRCh38 38.1/141 |
| Chromosome | 3 |
| Position | 53524975 |
| Gene | CACNA1D |
| is a | snp |
| is | mentioned by |
| dbSNP | rs3774426 |
| dbSNP (classic) | rs3774426 |
| ClinGen | rs3774426 |
| ebi | rs3774426 |
| HLI | rs3774426 |
| Exac | rs3774426 |
| Gnomad | rs3774426 |
| Varsome | rs3774426 |
| LitVar | rs3774426 |
| Map | rs3774426 |
| PheGenI | rs3774426 |
| Biobank | rs3774426 |
| 1000 genomes | rs3774426 |
| hgdp | rs3774426 |
| ensembl | rs3774426 |
| geneview | rs3774426 |
| scholar | rs3774426 |
| rs3774426 | |
| pharmgkb | rs3774426 |
| gwascentral | rs3774426 |
| openSNP | rs3774426 |
| 23andMe | rs3774426 |
| SNPshot | rs3774426 |
| SNPdbe | rs3774426 |
| MSV3d | rs3774426 |
| GWAS Ctlg | rs3774426 |
| GMAF | 0.2557 |
| Max Magnitude | 0 |
| ? | (C;C) (C;T) (T;T) | 28 |
|---|---|---|
|
| ||
rs3774426 is a SNP in the calcium channel, voltage-dependent, L type, alpha 1D subunit CACNA1D gene.
A study of 161 Japanese patients (85 men, 76 women) being treated for hypertension with L-type dCCBs (calcium channel blockers) concluded that individuals with rs3774426(C;C) genotypes responded better, as measured by lowered systolic and diastolic blood pressure readings.[PMID 19225208]
