rs3780422
From SNPedia
| Orientation | minus |
| Stabilized | minus |
| Make rs3780422(A;A) |
| Make rs3780422(A;G) |
| Make rs3780422(G;G) |
| Reference | GRCh38 38.1/141 |
| Chromosome | 9 |
| Position | 98380522 |
| Gene | GABBR2 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs3780422 |
| dbSNP (classic) | rs3780422 |
| ClinGen | rs3780422 |
| ebi | rs3780422 |
| HLI | rs3780422 |
| Exac | rs3780422 |
| Gnomad | rs3780422 |
| Varsome | rs3780422 |
| LitVar | rs3780422 |
| Map | rs3780422 |
| PheGenI | rs3780422 |
| Biobank | rs3780422 |
| 1000 genomes | rs3780422 |
| hgdp | rs3780422 |
| ensembl | rs3780422 |
| geneview | rs3780422 |
| scholar | rs3780422 |
| rs3780422 | |
| pharmgkb | rs3780422 |
| gwascentral | rs3780422 |
| openSNP | rs3780422 |
| 23andMe | rs3780422 |
| SNPshot | rs3780422 |
| SNPdbe | rs3780422 |
| MSV3d | rs3780422 |
| GWAS Ctlg | rs3780422 |
| GMAF | 0.3903 |
| Max Magnitude | 0 |
[PMID 15759211
] Associated with nicotine Dependence as part of several haplotypes, based on a study of 1,000+ subjects including both African-Americans and European-Americans.
The risk haplotype varies between populations. Among African-Americans, the haplotype C-C-G of rs2491397-rs2184026-rs3750344 had a significant positive association with nicotine dependence. Among European-Americans, for rs1435252-rs3780422-rs2779562-rs3750344, the C-A-C-A haplotype was positively associated with nicotine dependence while the T-A-T-A haplotype was negatively associated.[PMID 15759211]
