rs3807306
| Orientation | minus |
| Stabilized | minus |
| Make rs3807306(A;A) |
| Make rs3807306(A;C) |
| Make rs3807306(C;C) |
| Reference | GRCh38 38.1/141 |
| Chromosome | 7 |
| Position | 128940626 |
| Gene | IRF5 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs3807306 |
| dbSNP (classic) | rs3807306 |
| ClinGen | rs3807306 |
| ebi | rs3807306 |
| HLI | rs3807306 |
| Exac | rs3807306 |
| Gnomad | rs3807306 |
| Varsome | rs3807306 |
| LitVar | rs3807306 |
| Map | rs3807306 |
| PheGenI | rs3807306 |
| Biobank | rs3807306 |
| 1000 genomes | rs3807306 |
| hgdp | rs3807306 |
| ensembl | rs3807306 |
| geneview | rs3807306 |
| scholar | rs3807306 |
| rs3807306 | |
| pharmgkb | rs3807306 |
| gwascentral | rs3807306 |
| openSNP | rs3807306 |
| 23andMe | rs3807306 |
| SNPshot | rs3807306 |
| SNPdbe | rs3807306 |
| MSV3d | rs3807306 |
| GWAS Ctlg | rs3807306 |
| GMAF | 0.3494 |
| Max Magnitude | 0 |
| ? | (A;A) (A;C) (C;C) | 28 |
|---|---|---|
|
| ||
[PMID 18285424
] rs4728142, rs3807306 and a 5 bp insertion-deletion linked multiple sclerosis in three populations
[PMID 18288123] Associated with systemic lupus erythematosus (SLE) in African Americans.
[PMID 15657875] Polymorphisms in the tyrosine kinase 2 and interferon regulatory factor 5 genes are associated with systemic lupus erythematosus.
[PMID 17189288] Association of IRF5 in UK SLE families identifies a variant involved in polyadenylation.
[PMID 18668568] Association of the IRF5 risk haplotype with high serum interferon-alpha activity in systemic lupus erythematosus patients.
[PMID 19109131] Cutting edge: autoimmune disease risk variant of STAT4 confers increased sensitivity to IFN-alpha in lupus patients in vivo.
[PMID 19956648] Pathway analysis of GWAS provides new insights into genetic susceptibility to 3 inflammatory diseases.
[PMID 20479942] Genetic risk factors in lupus nephritis and IgA nephropathy--no support of an overlap.
[PMID 20603721] Genome-wide association filtering using a highly locus-specific transmission/disequilibrium test.
[PMID 20861862] Validation of IRF5 as multiple sclerosis risk gene: putative role in interferon beta therapy and human herpes virus-6 infection.
[PMID 23971939] IRF5, but not TLR4, DEFEB1, or VDR, is associated with the risk of ulcerative colitis in a Han Chinese population
| GWAS snp | |
|---|---|
| PMID | [PMID 21156761]
|
| Trait | Rheumatoid arthritis |
| Title | A genome-wide association study suggests contrasting associations in ACPA-positive versus ACPA-negative rheumatoid arthritis. |
| Risk Allele | |
| P-val | 3E-7 |
| Odds Ratio | 1.44 [1.25-1.66] |
[PMID 25564941] Association between genetic polymorphisms in Interferon Regulatory Factor 5 (IRF5) gene and Malaysian patients with Crohn's disease
[PMID 32328064] Autoimmunity-Related Risk Variants in PTPN22 and CTLA4 Are Associated With ME/CFS With Infectious Onset.
