rs4646437
| Orientation | minus |
| Stabilized | minus |
| Geno | Mag | Summary |
|---|---|---|
| (C;C) | 0 | common in complete genomics |
| Make rs4646437(C;T) |
| Make rs4646437(T;T) |
| Reference | GRCh38.p2 38.2/146 |
| Chromosome | 7 |
| Position | 99767460 |
| Gene | CYP3A4 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs4646437 |
| dbSNP (classic) | rs4646437 |
| ClinGen | rs4646437 |
| ebi | rs4646437 |
| HLI | rs4646437 |
| Exac | rs4646437 |
| Gnomad | rs4646437 |
| Varsome | rs4646437 |
| LitVar | rs4646437 |
| Map | rs4646437 |
| PheGenI | rs4646437 |
| Biobank | rs4646437 |
| 1000 genomes | rs4646437 |
| hgdp | rs4646437 |
| ensembl | rs4646437 |
| geneview | rs4646437 |
| scholar | rs4646437 |
| rs4646437 | |
| pharmgkb | rs4646437 |
| gwascentral | rs4646437 |
| openSNP | rs4646437 |
| 23andMe | rs4646437 |
| SNPshot | rs4646437 |
| SNPdbe | rs4646437 |
| MSV3d | rs4646437 |
| GWAS Ctlg | rs4646437 |
| GMAF | 0.2713 |
| Max Magnitude | 0 |
| ? | (C;C) (C;T) (T;T) | 28 |
|---|---|---|
|
| ||
[PMID 19801957] The P450 oxidoreductase genotype is associated with CYP3A activity in vivo as measured by the midazolam phenotyping test
[PMID 17465708] Sex-dependent genetic markers of CYP3A4 expression and activity in human liver microsomes.
[PMID 18825162
] Prediction of CYP3A4 enzyme activity using haplotype tag SNPs in African Americans.
[PMID 18978522] CYP3A7, CYP3A5, CYP3A4, and ABCB1 genetic polymorphisms, cyclosporine concentration, and dose requirement in transplant recipients.
[PMID 23609392] Pharmacogenetic study on risperidone long-acting injection: influence of cytochrome P450 2D6 and pregnane X receptor on risperidone exposure and drug-induced side-effects.
[PMID 26810136] Sunitinib-induced hypertension in CYP3A4 rs4646437 A-allele carriers with metastatic renal cell carcinoma.
[PMID 28787260] Genetic variants in 5p13.2 and 7q21.1 are associated with treatment for benign prostatic hyperplasia with the α-adrenergic receptor antagonist.
[PMID 30065912] Variants of FasL and ABCC5 are predictive of outcome after chemotherapy-based treatment in osteosarcoma.
[PMID 31799230] Effects of CYP3A4 Polymorphisms on Drug Addiction Risk Among the Chinese Han Population.
[PMID 32464168] CYP3A4 genetic variants are associated with susceptibility of non-small cell lung cancer in a Shaanxi Han population.
