rs6220
| Orientation | plus |
| Stabilized | plus |
| Geno | Mag | Summary |
|---|---|---|
| (G;G) | 0 | common in clinvar |
| Make rs6220(A;A) |
| Make rs6220(A;G) |
| Reference | GRCh38 38.1/141 |
| Chromosome | 12 |
| Position | 102400737 |
| Gene | IGF1, LOC105369942 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs6220 |
| dbSNP (classic) | rs6220 |
| ClinGen | rs6220 |
| ebi | rs6220 |
| HLI | rs6220 |
| Exac | rs6220 |
| Gnomad | rs6220 |
| Varsome | rs6220 |
| LitVar | rs6220 |
| Map | rs6220 |
| PheGenI | rs6220 |
| Biobank | rs6220 |
| 1000 genomes | rs6220 |
| hgdp | rs6220 |
| ensembl | rs6220 |
| geneview | rs6220 |
| scholar | rs6220 |
| rs6220 | |
| pharmgkb | rs6220 |
| gwascentral | rs6220 |
| openSNP | rs6220 |
| 23andMe | rs6220 |
| SNPshot | rs6220 |
| SNPdbe | rs6220 |
| MSV3d | rs6220 |
| GWAS Ctlg | rs6220 |
| GMAF | 0.3526 |
| Max Magnitude | 0 |
[PMID 17911177] Implications for prostate cancer of IGF1 the TCC haplotype and the rs6220 SNP were associated with elevated levels of circulating IGF1 (p = 0.001 and <0.0001, respectively)
[PMID 19784788] Association of IGF1 and IGFBP3 polymorphisms with colorectal polyps and colorectal cancer risk
[PMID 21552154] Common genetic variation in the IGF1 associates with maximal force output
[PMID 18064566] Common genetic variation in the IGF-1 gene, serum IGF-I levels and breast density.
[PMID 18199734
] IGF-I and IGF-II genetic variation and breast cancer risk in Chinese women: results from the Shanghai Breast Cancer Study.
[PMID 18398029] Genetic polymorphisms involved in insulin-like growth factor (IGF) pathway in relation to mammographic breast density and IGF levels.
[PMID 18562769] Genetic variation in insulin-like growth factors and brain tumor risk.
[PMID 18772892] Can genes for mammographic density inform cancer aetiology?
[PMID 20302654] Genotypes and haplotypes in the insulin-like growth factors, their receptors and binding proteins in relation to plasma metabolic levels and mammographic density.
[PMID 21113804] IGF1 htSNPs in relation to IGF-1 levels in young women from high-risk breast cancer families: implications for early-onset breast cancer.
[PMID 21791631] Pharmacogenetic angiogenesis profiling for first-line Bevacizumab plus oxaliplatin-based chemotherapy in patients with metastatic colorectal cancer.
[PMID 23180020] Association of a common genetic variant of the IGF-1 gene with event-free survival in patients with HER2-positive breast cancer
[PMID 23530598] Insulin-like growth factor-1 genotypes and haplotypes influence the survival of prostate cancer patients with bone metastasis at initial diagnosis
[PMID 28315227] Insulin-like growth factor 1 gene polymorphism in women with breast cancer.
| ClinVar | |
|---|---|
| Risk | rs6220(A;A) |
| Alt | rs6220(A;A) |
| Reference | Rs6220(G;G) |
| Significance | Non-pathogenic |
| Disease | Insulin-like growth factor I deficiency |
| Variation | info |
| Gene | IGF1 |
| CLNDBN | Insulin-like growth factor I deficiency |
| Reversed | 0 |
| HGVS | NC_000012.11:g.102794515G>A |
| CLNSRC | |
| CLNACC | RCV000348790.1, |
[PMID 29172265] SNPs in the Insulin-Like Growth Factor Gene and Obesity Impact on Colorectal Cancer in Egyptians
