rs6837293
From SNPedia
| Orientation | plus |
| Stabilized | plus |
| Geno | Mag | Summary |
|---|---|---|
| (C;C) | 0 | |
| (T;T) | 2.7 | If Taiwanese, you might be 2.72 times more likely to develop gout |
| Make rs6837293(C;T) |
| Reference | GRCh38 38.1/141 |
| Chromosome | 4 |
| Position | 81141777 |
| Gene | PRKG2 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs6837293 |
| dbSNP (classic) | rs6837293 |
| ClinGen | rs6837293 |
| ebi | rs6837293 |
| HLI | rs6837293 |
| Exac | rs6837293 |
| Gnomad | rs6837293 |
| Varsome | rs6837293 |
| LitVar | rs6837293 |
| Map | rs6837293 |
| PheGenI | rs6837293 |
| Biobank | rs6837293 |
| 1000 genomes | rs6837293 |
| hgdp | rs6837293 |
| ensembl | rs6837293 |
| geneview | rs6837293 |
| scholar | rs6837293 |
| rs6837293 | |
| pharmgkb | rs6837293 |
| gwascentral | rs6837293 |
| openSNP | rs6837293 |
| 23andMe | rs6837293 |
| SNPshot | rs6837293 |
| SNPdbe | rs6837293 |
| MSV3d | rs6837293 |
| GWAS Ctlg | rs6837293 |
| GMAF | 0.4642 |
| Max Magnitude | 2.7 |
| ? | (C;C) (C;T) (T;T) | 28 |
|---|---|---|
|
| ||
Two SNPs in the cGMP-dependent protein kinase II (cGK II) PRKG2 gene, rs7688672 and rs6837293, were found to be associated in 148 matched Taiwanese case:control subjects with gout disease using a recessive model after adjustment of hyperuricemia (odds ratio 2.72, CI: 1.13-6.54).[PMID 18678579]
Note that this was a relatively small study and since the original 2009 publication cited there has not been a publication confirming or replicating the finding.
