rs7019241
From SNPedia
| Orientation | plus |
| Stabilized | plus |
| Geno | Mag | Summary |
|---|---|---|
| (C;C) | 0 | average |
| (C;T) | reduced risk for AD? | |
| (G;G) | 0 | |
| (T;T) | reduced risk for AD? |
| Reference | GRCh38 38.1/141 |
| Chromosome | 9 |
| Position | 86078545 |
| Gene | GOLM1 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs7019241 |
| dbSNP (classic) | rs7019241 |
| ClinGen | rs7019241 |
| ebi | rs7019241 |
| HLI | rs7019241 |
| Exac | rs7019241 |
| Gnomad | rs7019241 |
| Varsome | rs7019241 |
| LitVar | rs7019241 |
| Map | rs7019241 |
| PheGenI | rs7019241 |
| Biobank | rs7019241 |
| 1000 genomes | rs7019241 |
| hgdp | rs7019241 |
| ensembl | rs7019241 |
| geneview | rs7019241 |
| scholar | rs7019241 |
| rs7019241 | |
| pharmgkb | rs7019241 |
| gwascentral | rs7019241 |
| openSNP | rs7019241 |
| 23andMe | rs7019241 |
| SNPshot | rs7019241 |
| SNPdbe | rs7019241 |
| MSV3d | rs7019241 |
| GWAS Ctlg | rs7019241 |
| GMAF | 0.2635 |
| Max Magnitude | 0 |
| ? | (C;C) (C;T) (T;T) | 28 |
|---|---|---|
|
| ||
rs7019241, a SNP in the GOLM1 gene, is associated with reduced risk for Alzheimer's disease in a study of ~1100 Canadian patients. The protective allele appears to be rs10868366(T), giving an odds ratio of 0.54 (CI: 0.38 - 0.75). [PMID 17998437]
[PMID 19204163
] GAB2 as an Alzheimer disease susceptibility gene: follow-up of genomewide association results.
[PMID 19749441] GOLPH2 gene markers are not associated with Alzheimer's disease in a sample of the Spanish population.
[PMID 20574532] Intermediate phenotypes identify divergent pathways to Alzheimer's disease.
[PMID 22167654] Association studies of 19 candidate SNPs with sporadic Alzheimer's disease in the North Chinese Han population.
