rs706778
| Orientation | minus |
| Stabilized | minus |
| Make rs706778(A;A) |
| Make rs706778(A;G) |
| Make rs706778(G;G) |
| Reference | GRCh38 38.1/142 |
| Chromosome | 10 |
| Position | 6056986 |
| Gene | IL2RA |
| is a | snp |
| is | mentioned by |
| dbSNP | rs706778 |
| dbSNP (classic) | rs706778 |
| ClinGen | rs706778 |
| ebi | rs706778 |
| HLI | rs706778 |
| Exac | rs706778 |
| Gnomad | rs706778 |
| Varsome | rs706778 |
| LitVar | rs706778 |
| Map | rs706778 |
| PheGenI | rs706778 |
| Biobank | rs706778 |
| 1000 genomes | rs706778 |
| hgdp | rs706778 |
| ensembl | rs706778 |
| geneview | rs706778 |
| scholar | rs706778 |
| rs706778 | |
| pharmgkb | rs706778 |
| gwascentral | rs706778 |
| openSNP | rs706778 |
| 23andMe | rs706778 |
| SNPshot | rs706778 |
| SNPdbe | rs706778 |
| MSV3d | rs706778 |
| GWAS Ctlg | rs706778 |
| GMAF | 0.4844 |
| Max Magnitude | 0 |
| ? | (A;A) (A;G) (G;G) | 28 |
|---|---|---|
|
| ||
rs706778 is mentioned as being strongly associated with type-1 diabetes in [PMID 17554300
]
| GWAS snp | |
|---|---|
| PMID | [PMID 20453842]
|
| Trait | Rheumatoid arthritis |
| Title | Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk lock |
| Risk Allele | T |
| P-val | 1E-11 |
| Odds Ratio | 1.14 [NR] |
[PMID 20615141] Association of the Protein Tyrosine Phosphatase Nonreceptor 22 Haplotypes with Autoimmune Thyroid Disease in the Japanese Population
[PMID 17395754] Toward further mapping of the association between the IL2RA locus and type 1 diabetes.
[PMID 18556337] Impact of diabetes susceptibility loci on progression from pre-diabetes to diabetes in at-risk individuals of the diabetes prevention trial-type 1 (DPT-1).
[PMID 18776148] Joint genetic susceptibility to type 1 diabetes and autoimmune thyroiditis: from epidemiology to mechanisms.
[PMID 19106270] Genetic association between the interleukin-2 receptor-alpha gene and mode of onset of type 1 diabetes in the Japanese population.
[PMID 19956099] The type I diabetes association of the IL2RA locus.
[PMID 19956101] Overview of the Rapid Response data.
[PMID 22328738] Comprehensive assessment of rheumatoid arthritis susceptibility loci in a large psoriatic arthritis cohort.
[PMID 22897480] Investigation of selected cytokine genes suggests that IL2RA and the TNF/LTA locus are risk factors for severe alopecia areata.
[PMID 23972291] Polymorphisms in the IL2RA and IL2RB genes in inflammatory bowel disease risk
| GWAS snp | |
|---|---|
| PMID | [PMID 24390342]
|
| Trait | Rheumatoid arthritis |
| Title | Genetics of rheumatoid arthritis contributes to biology and drug discovery. |
| Risk Allele | T |
| P-val | 5E-15 |
| Odds Ratio | 1.12 [1.09-1.15] |
