rs8187710
| Orientation | plus |
| Stabilized | plus |
| Geno | Mag | Summary |
|---|---|---|
| (G;G) | 0 | common on affy axiom data |
| Make rs8187710(A;A) |
| Make rs8187710(A;G) |
| Reference | GRCh38 38.1/142 |
| Chromosome | 10 |
| Position | 99851537 |
| Gene | ABCC2 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs8187710 |
| dbSNP (classic) | rs8187710 |
| ClinGen | rs8187710 |
| ebi | rs8187710 |
| HLI | rs8187710 |
| Exac | rs8187710 |
| Gnomad | rs8187710 |
| Varsome | rs8187710 |
| LitVar | rs8187710 |
| Map | rs8187710 |
| PheGenI | rs8187710 |
| Biobank | rs8187710 |
| 1000 genomes | rs8187710 |
| hgdp | rs8187710 |
| ensembl | rs8187710 |
| geneview | rs8187710 |
| scholar | rs8187710 |
| rs8187710 | |
| pharmgkb | rs8187710 |
| gwascentral | rs8187710 |
| openSNP | rs8187710 |
| 23andMe | rs8187710 |
| SNPshot | rs8187710 |
| SNPdbe | rs8187710 |
| MSV3d | rs8187710 |
| GWAS Ctlg | rs8187710 |
| GMAF | 0.06979 |
| Max Magnitude | 0 |
| ? | (A;A) (A;G) (G;G) | 28 |
|---|---|---|
|
| ||
[PMID 19842932] Association between ABCC2 polymorphism and lopinavir accumulation in peripheral blood mononuclear cells of HIV-infected patients
[PMID 17997497] Association of the multidrug-resistance-associated protein gene (ABCC2) variants with intrahepatic cholestasis of pregnancy.
[PMID 18176959
] Increased susceptibility for intrahepatic cholestasis of pregnancy and contraceptive-induced cholestasis in carriers of the 1331T>C polymorphism in the bile salt export pump.
[PMID 18395921] Role of ABCC2 common variants in intrahepatic cholestasis of pregnancy.
[PMID 18926681] Polymorphisms of MRP2 (ABCC2) are associated with susceptibility to nonalcoholic fatty liver disease.
[PMID 22027652] Functional defect caused by the 4544G>A SNP in ABCC2: potential impact for drug cellular disposition.
[PMID 23069858] Impact of ABCC2 polymorphisms on high-dose methotrexate pharmacokinetics in patients with lymphoid malignancy.
| ClinVar | |
|---|---|
| Risk | rs8187710(A;A) |
| Alt | rs8187710(A;A) |
| Reference | Rs8187710(G;G) |
| Significance | Probable-non-pathogenic |
| Disease | Dubin-Johnson syndrome |
| Variation | info |
| Gene | ABCC2 |
| CLNDBN | Dubin-Johnson syndrome |
| Reversed | 0 |
| HGVS | NC_000010.10:g.101611294G>A |
| CLNSRC | |
| CLNACC | RCV000329504.1, |
[PMID 31539757] The role of single-nucleotide polymorphism (SNPs) in toxicity of induction chemotherapy based on cisplatin and paclitaxel in patients with advanced head and neck cancer.
