rs917997
| Orientation | minus |
| Stabilized | minus |
| Geno | Mag | Summary |
|---|---|---|
| (G;G) | 0 |
| Make rs917997(A;A) |
| Make rs917997(A;G) |
| Reference | GRCh38 38.1/141 |
| Chromosome | 2 |
| Position | 102454108 |
| Gene | IL18RAP |
| is a | snp |
| is | mentioned by |
| dbSNP | rs917997 |
| dbSNP (classic) | rs917997 |
| ClinGen | rs917997 |
| ebi | rs917997 |
| HLI | rs917997 |
| Exac | rs917997 |
| Gnomad | rs917997 |
| Varsome | rs917997 |
| LitVar | rs917997 |
| Map | rs917997 |
| PheGenI | rs917997 |
| Biobank | rs917997 |
| 1000 genomes | rs917997 |
| hgdp | rs917997 |
| ensembl | rs917997 |
| geneview | rs917997 |
| scholar | rs917997 |
| rs917997 | |
| pharmgkb | rs917997 |
| gwascentral | rs917997 |
| openSNP | rs917997 |
| 23andMe | rs917997 |
| SNPshot | rs917997 |
| SNPdbe | rs917997 |
| MSV3d | rs917997 |
| GWAS Ctlg | rs917997 |
| GMAF | 0.2773 |
| Max Magnitude | 0 |
| ? | (A;A) (A;G) (G;G) | 28 |
|---|---|---|
|
| ||
[PMID 19693089] Four novel coeliac disease regions replicated in an association study of a Swedish-Norwegian family cohort
[PMID 19542083] Association of IL18RAP and CCR3 with coeliac disease in the Spanish population
| GWAS snp | |
|---|---|
| PMID | [PMID 20190752 ]
|
| Trait | Celiac disease |
| Title | Multiple common variants for celiac disease influencing immune gene expression |
| Risk Allele | A |
| P-val | 1E-15 |
| Odds Ratio | 1.19 [1.14-1.25] |
[PMID 22664470] Genes of the Interleukin-18 Pathway Are Associated With Susceptibility to Barrett's Esophagus and Esophageal Adenocarcinoma
[PMID 18311140] Newly identified genetic risk variants for celiac disease related to the immune response.
[PMID 18587394] Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease.
[PMID 18713140] Translational mini-review series on the immunogenetics of gut disease: immunogenetics of coeliac disease.
[PMID 19068216] Investigation of Crohn's disease risk loci in ulcerative colitis further defines their molecular relationship.
[PMID 19073967] Shared and distinct genetic variants in type 1 diabetes and celiac disease.
[PMID 19103669] Association study of the IL18RAP locus in three European populations with coeliac disease.
[PMID 19468064] Parasites represent a major selective force for interleukin genes and shape the genetic predisposition to autoimmune conditions.
[PMID 19557189] Identifying relationships among genomic disease regions: predicting genes at pathogenic SNP associations and rare deletions.
[PMID 20353565] Allelic variants of IL1R1 gene associate with severe hand osteoarthritis.
[PMID 21304977] An investigation of genome-wide studies reported susceptibility loci for ulcerative colitis shows limited replication in north Indians.
| GWAS snp | |
|---|---|
| PMID | [PMID 23128233]
|
| Trait | Inflammatory bowel disease |
| Title | Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease. |
| Risk Allele | T |
| P-val | 3E-20 |
| Odds Ratio | 1.10 [1.067-1.14] |
[PMID 24871462] Coeliac disease-associated polymorphisms influence thymic gene expression
[PMID 26566691] Polymorphisms of ST2-IL18R1-IL18RAP gene cluster: a new risk for autoimmune thyroid diseases
[PMID 32284404] The T1D-associated lncRNA Lnc13 modulates human pancreatic β cell inflammation by allele-specific stabilization of STAT1 mRNA.
