| Geno
|
Mag
|
Summary
|
| (C;C)
|
|
more likely to gain weight if taking olanzapine
|
| (C;T)
|
|
more likely to gain weight if taking olanzapine
|
| (T;T)
|
0
|
normal
|
rs4765623 is a SNP in the scavenger receptor class B, member 1 SCARB1 gene.
In a study of 67 mostly Caucasian patients prescribed the atypical antipsychotic olanzapine, carriers of a rs4765623(C) allele were more likely to gain significant weight compared to rs4765623(T;T) carriers, as assessed by physiogenomic analysis of corresponding weight profiles. Two other SNPs, rs5092 and rs7412, were also significantly associated with weight profiles in these patients.[PMID 17199131]
| GWAS snp
|
| PMID
|
[PMID 21131975 ]
|
| Trait
|
|
| Title
|
Genome-wide association study of renal cell carcinoma identifies two susceptibility loci on 2p21 and 11q13.3
|
| Risk Allele
|
|
| P-val
|
3E-8
|
| Odds Ratio
|
1.1500 [1.09-1.20]
|
[PMID 22131124] Chromosome 11q13.3 variant modifies renal cell cancer risk in a Chinese population
[PMID 18072279] Combining fMRI and SNP data to investigate connections between brain function and genetics using parallel ICA.
]
