rs5068
| Orientation | minus |
| Stabilized | minus |
| Geno | Mag | Summary |
|---|---|---|
| (T;T) | 0 |
| Make rs5068(C;C) |
| Make rs5068(C;T) |
| Reference | GRCh38 38.1/142 |
| Chromosome | 1 |
| Position | 11845917 |
| Gene | NPPA, NPPA-AS1 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs5068 |
| dbSNP (classic) | rs5068 |
| ClinGen | rs5068 |
| ebi | rs5068 |
| HLI | rs5068 |
| Exac | rs5068 |
| Gnomad | rs5068 |
| Varsome | rs5068 |
| LitVar | rs5068 |
| Map | rs5068 |
| PheGenI | rs5068 |
| Biobank | rs5068 |
| 1000 genomes | rs5068 |
| hgdp | rs5068 |
| ensembl | rs5068 |
| geneview | rs5068 |
| scholar | rs5068 |
| rs5068 | |
| pharmgkb | rs5068 |
| gwascentral | rs5068 |
| openSNP | rs5068 |
| 23andMe | rs5068 |
| SNPshot | rs5068 |
| SNPdbe | rs5068 |
| MSV3d | rs5068 |
| GWAS Ctlg | rs5068 |
| GMAF | 0.03076 |
| Max Magnitude | 0 |
| ? | (C;C) (C;T) (T;T) | 28 |
|---|---|---|
|
| ||
A study of ~15,000 Europeans found that increased circulating natriuretic peptide and thus lower blood pressure and hypertension were associated with SNPs rs17376328(A), rs5068, rs198358(C), rs632793(G)
[PMID 19219041
]23andMe blog
[PMID 22496669] A Genome-Wide Screen for Genetic Variants That Modify the Recruitment of REST to Its Target Genes
[PMID 19439027] Dissecting complex traits: recent advances in hypertension genomics.
[PMID 20407391] Association of common variants in NPPA and NPPB with blood pressure does not translate into kidney damage in a general population study.
[PMID 21273288] Genome-wide association analysis and fine mapping of NT-proBNP level provide novel insight into the role of the MTHFR-CLCN6-NPPA-NPPB gene cluster.
[PMID 21276798] Association of genetic variation in the natriuretic peptide system with cardiovascular outcomes.
[PMID 21798427] A genetic variant of the atrial natriuretic peptide gene is associated with cardiometabolic protection in the general community.
[PMID 22504314] Orthostatic hypotension and novel blood pressure-associated gene variants: Genetics of Postural Hemodynamics (GPH) Consortium.
[PMID 23799939] A genetic variant of the atrial natriuretic peptide gene is associated with left ventricular hypertrophy in a non-diabetic population -- the Malmo preventive project study
[PMID 23315043] Common genetic variants of the natriuretic peptide gene locus are not associated with heart failure risk in participants in the EPIC-Norfolk study
[PMID 31821404] Orthostatic hypotension and novel blood pressure associated gene variants in older adults: data from the TILDA Study.
