rs7501939
| Orientation | plus |
| Stabilized | plus |
| Geno | Mag | Summary |
|---|---|---|
| (T;C) |
| Make rs7501939(C;C) |
| Make rs7501939(C;T) |
| Make rs7501939(T;T) |
| Reference | GRCh38 38.1/141 |
| Chromosome | 17 |
| Position | 37741165 |
| Gene | HNF1B |
| is a | snp |
| is | mentioned by |
| dbSNP | rs7501939 |
| dbSNP (classic) | rs7501939 |
| ClinGen | rs7501939 |
| ebi | rs7501939 |
| HLI | rs7501939 |
| Exac | rs7501939 |
| Gnomad | rs7501939 |
| Varsome | rs7501939 |
| LitVar | rs7501939 |
| Map | rs7501939 |
| PheGenI | rs7501939 |
| Biobank | rs7501939 |
| 1000 genomes | rs7501939 |
| hgdp | rs7501939 |
| ensembl | rs7501939 |
| geneview | rs7501939 |
| scholar | rs7501939 |
| rs7501939 | |
| pharmgkb | rs7501939 |
| gwascentral | rs7501939 |
| openSNP | rs7501939 |
| 23andMe | rs7501939 |
| SNPshot | rs7501939 |
| SNPdbe | rs7501939 |
| MSV3d | rs7501939 |
| GWAS Ctlg | rs7501939 |
| GMAF | 0.3861 |
| Max Magnitude | 0 |
| ? | (C;C) (C;T) (T;T) | 28 |
|---|---|---|
|
| ||
[1] related to Prostate cancer and Type-2 diabetes
[PMID 18701471
] The increased risk associated with rs7501939 and the closely linked rs4430796 is approximately doubled in individuals hereditarily predisposed to develop early-onset prostate cancer, based on a study of ~1,000 men.
[PMID 19998368] rs7501939 identified as one of three HNF1B gene SNPs associated with decreased risk for prostate cancer in two large prospective studies
cancer-genetics these SNPs influence genetic risk for prostate cancer
- the haplotype rs6983267 rs1016343 rs4242384
- rs7501939
- rs1859962
- rs2660753
- rs9364554
- rs6465657
- rs10993994
- rs7931342
- rs2735839
- rs5945619
- rs10993994
| GWAS snp | |
|---|---|
| PMID | [PMID 18264097] |
| Trait | Prostate cancer |
| Title | Multiple newly identified loci associated with prostate cancer susceptibility |
| Risk Allele | C |
| P-val | 8.9999999999999996E-12 |
| Odds Ratio | 1.41 [NR] |
| GWAS snp | |
|---|---|
| PMID | [PMID 19767753]
|
| Trait | Prostate cancer |
| Title | Identification of seven new prostate cancer susceptibility loci through a genome-wide association study |
| Risk Allele | C |
| P-val | 3E-18 |
| Odds Ratio | NR NR |
| GWAS snp | |
|---|---|
| PMID | [PMID 20676098] |
| Trait | |
| Title | Genome-wide association study identifies five new susceptibility loci for prostate cancer in the Japanese population |
| Risk Allele | |
| P-val | 1E-12 |
| Odds Ratio | None None |
| GWAS snp | |
|---|---|
| PMID | [PMID 21743057]
|
| Trait | |
| Title | Genome-wide association study identifies new prostate cancer susceptibility loci. |
| Risk Allele | C |
| P-val | 0.000002 |
| Odds Ratio | 1.1900 [1.11-1.28] |
[PMID 22299039] HNF1B and Endometrial Cancer Risk: Results from the PAGE study
[PMID 18426861] Association analysis of type 2 diabetes Loci in type 1 diabetes.
[PMID 18974127] Association study of prostate cancer susceptibility variants with risks of invasive ovarian, breast, and colorectal cancer.
[PMID 19096518] Novel association of HK1 with glycated hemoglobin in a non-diabetic population: a genome-wide evaluation of 14,618 participants in the Women's Genome Health Study.
[PMID 19168595] Common variants of hepatocyte nuclear factor 1beta are associated with type 2 diabetes in a Chinese population.
[PMID 19401414] Confirmation of multiple risk Loci and genetic impacts by a genome-wide association study of type 2 diabetes in the Japanese population.
[PMID 19455305] No association of multiple type 2 diabetes loci with type 1 diabetes.
[PMID 20509872] Implication of genetic variants near SLC30A8, HHEX, CDKAL1, CDKN2A/B, IGF2BP2, FTO, TCF2, KCNQ1, and WFS1 in type 2 diabetes in a Chinese population.
[PMID 20690139] Meta-analysis of genome-wide and replication association studies on prostate cancer.
[PMID 21278902] Genetic risk profiling for prediction of type 2 diabetes.
[PMID 21390317] Characterizing associations and SNP-environment interactions for GWAS-identified prostate cancer risk markers--results from BPC3.
[PMID 24422606] Assessment of Association between Common Variants at 17q12 and Prostate Cancer Risk-Evidence from Serbian Population and Meta-Analysis
[PMID 27437873] A common variant within the HNF1B gene is associated with overall survival of multiple myeloma patients: Results from the IMMEnSE consortium and meta-analysis.
