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rs7395662

From SNPedia

Orientationplus
Stabilizedplus
Make rs7395662(A;A)
Make rs7395662(A;G)
Make rs7395662(G;G)
ReferenceGRCh38 38.1/141
Chromosome11
Position48497341
GeneOR4A46P
is asnp
is mentioned by
dbSNPrs7395662
dbSNP (classic)rs7395662
ClinGenrs7395662
ebirs7395662
HLIrs7395662
Exacrs7395662
Gnomadrs7395662
Varsomers7395662
LitVarrs7395662
Maprs7395662
PheGenIrs7395662
Biobankrs7395662
1000 genomesrs7395662
hgdprs7395662
ensemblrs7395662
geneviewrs7395662
scholarrs7395662
googlers7395662
pharmgkbrs7395662
gwascentralrs7395662
openSNPrs7395662
23andMers7395662
SNPshotrs7395662
SNPdbers7395662
MSV3drs7395662
GWAS Ctlgrs7395662
GMAF0.4619
Max Magnitude0
? (A;A) (A;G) (G;G) 28


per the 23andMe blog, the minor allele of this SNP (A) was associated with decreased LDL cholesterol, increased HDL cholesterol and increased triglycerides

SNP Rarer allele LDL HDL TG
rs6544713 T +
rs2650000 A +
rs471364 C -
rs1800961 T -
rs7679 C - +
rs2967605 T -
rs2409722 T -
rs10903129 A - - -
rs6756629 A - + -
rs12670798 C + + +
rs7395662 A - + +
rs174570 T - - +
rs2271293 A - + -
rs2624265 C +
rs2167079 T +
rs9891572 T +
rs4844614 T +
rs5031002 G +
GWAS snp
PMID [PMID 19060911OA-icon.png]
Trait HDL cholesterol
Title Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts
Risk Allele G
P-val 6E-11
Odds Ratio 0.07 [NR] SD decrease



[PMID 19041386OA-icon.png] Genetic-epidemiological evidence on genes associated with HDL cholesterol levels: a systematic in-depth review.


[PMID 19951432OA-icon.png] Analysis of recently identified dyslipidemia alleles reveals two loci that contribute to risk for carotid artery disease.


[PMID 20502693OA-icon.png] Genetics and beyond--the transcriptome of human monocytes and disease susceptibility.


[PMID 21304891OA-icon.png] A study of CNVs as trait-associated polymorphisms and as expression quantitative trait loci.



[PMID 26209006OA-icon.png] Associations of lipid levels susceptibility loci with coronary artery disease in Chinese population


[PMID 27070640OA-icon.png] MADD-FOLH1 Polymorphisms and Their Haplotypes with Serum Lipid Levels and the Risk of Coronary Heart Disease and Ischemic Stroke in a Chinese Han Population